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What is Project Twenty21?
- A UK-based patient registry and observational study run by Drug Science
- Launched in 2019 to generate real-world evidence on medical cannabis from UK patients
- Enrolled thousands of patients across multiple conditions and product types
- Represents one of the most comprehensive medical cannabis datasets in Europe
Project Twenty21 is building the UK-specific evidence base that will ultimately inform NHS commissioning, NICE guidelines, and prescribing frameworks.
Key Findings
- Statistically significant improvements in quality of life across the majority of enrolled patients
- Reductions in pain, anxiety, and sleep disturbance scores
- High proportions of patients reducing other medications including opioids and sleep aids
- Generally favourable safety profile — most adverse events mild and transient
The real-world evidence from Project Twenty21 directly supports the case for broader patient access to medical cannabis, including via the NHS.
